Altered presence of extra cellular matrix components in murine skin cancer: Modulation by Azadirachta indica leaf extract
نویسندگان
چکیده
منابع مشابه
Azadirachta indica leaf extract modulates initiation phase of murine forestomach tumorigenesis.
The effects of aqueous Azadirachta indica leaf extract (AAILE) on benzo(a)pyrene [B(a)P]-induced forestomach tumorigenesis, B(a)P-DNA adduct formation and certain parameters of carcinogen biotransformation system in mice have been reported earlier from our laboratory. In this study, the effects of AAILE on the enzymes of B(a)P biotransformation, which play crucial role in initiation of chemical...
متن کاملExtract of Azadirachta indica (Neem) Leaf Induces Apoptosis in 4T1 Breast Cancer BALB/c Mice
OBJECTIVE Azadirachta indica (Neem) has been used traditionally for many centuries. Some impressive therapeutic qualities have been discovered. However, the therapeutic effect of neem leaf extract in 4T1 breast cancer has not been documented. The purpose of the present study is to investigate the therapeutic effect of ethanolic Neem leaf extract in an in vivo 4T1 breast cancer model in mice. ...
متن کاملNeem (Azadirachta indica L.) leaf extract deteriorates oocyte quality by inducing ROS-mediated apoptosis in mammals
Neem (Azadirachta indica L.) leaf has been widely used in ayurvedic system of medicine for fertility regulation for a long time. The molecular mechanism by which neem leaf regulates female fertility remains poorly understood. Animal studies suggest that aqueous neem leaf extract (NLE) induces reactive oxygen species (ROS) - mediated granulosa cell apoptosis. Granulosa cell apoptosis deprives oo...
متن کاملAzadirachta indica leaf extract induces resistance in sesame against Alternaria leaf spot disease
Induced resistance is an important component of disease-resistance response of plants, and is accompanied by increased capability for activating defense responses upon pathogen ingress or elicitor treatment. Aqueous leaf extract of neem (Azadirachta indica Juss.) provided the control of Alternaria leaf spot pathogen (Alternaria sesami) of sesame (Sesamum indicum L: Syn. S. orientale L). Treatme...
متن کاملextract of azadirachta indica (neem) leaf induces apoptosis in 4t1 breast cancer balb/c mice
objective: azadirachta indica (neem) has been used traditionally for many centuries. some impressive therapeutic qualities have been discovered. however, the therapeutic effect of neem leaf extract in 4t1 breast cancer has not been documented. the purpose of the present study is to investigate the therapeutic effect of ethanolic neem leaf extract in an in vivo 4t1 breast cancer model in mice. m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Traditional and Complementary Medicine
سال: 2021
ISSN: 2225-4110
DOI: 10.1016/j.jtcme.2020.03.006